Clomiphene Citrate for Men Clomid Male Infertility Treatment Male Hormone Replacement Therapy
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- Model NO.: CAS: 50-41-9
- Customized: Non-Customized
- Suitable for: Elderly, Adult
- Purity: >99%
- Clomid: Commonly Referenced Brand Name for Clomiphene
- Assay: 99.5%
- Specification: USP
- HS Code: 8888
- Powder: Yes
- Certification: GMP, ISO 9001, USP, BP
- State: Powder
- Synonyms: Clomid ; Clomiphene Citrate
- Appearance: White or Milky White Crystalline Powder
- Trademark: LSW
- Origin: China
Quick reviews of Clomiphene citrate:
Clomifene citrate is a drug treatment that stimulates your ovaries to release eggs.
Ovulation stimulation using clomifene citrate is a well-established, effective treatment (Brown et al 2009). Clomifene citrate is the most widely used of all fertility drugs.
Clomiphene citrate is used for post cycle therapy
Clomid Male Infertility Treatments - What You Need to Know
What are Clomid male infertility treatments? Anyone who is navigating the road of infertility probably recognizes Clomid as a treatment for women who have a difficulty ovulating. But the fact is that this unlikely treatment is also common for men who have infertility related to sperm quality and motility.
Clomid is a medication which is commonly used as a treatment for female infertility. It can also be used to treat some cases of male infertility. In women, Clomid is used to induce ovulation or to produce multiple eggs. When Clomid is prescribed for men, it can increase your testosterone level and improve your sperm count.
Just as women have low levels of testosterone in their bodies, men have certain female hormones in their bodies. Men also produce FSH and LH, which stimulate the production of testosterone and sperm. In men, FSH stimulates the testes to produce sperm similar to the way it stimulates the ovaries to produce eggs in women. Low FSH and LH levels can sometimes be a cause of low sperm counts.
Here's your guide to Clomiphene citrate for men:
Clomiphene citrate makes more swimmers
Low sperm count is a common cause of male infertility. In fact, there is a laundry list of reasons a man might have fewer swimmers than normal: injury to the testicles, hormonal problems, medications, smoking, and alcohol abuse, just to name a few. Men who've had vasectomy reversals may also experience low sperm counts.
Some reproductive specialists prescribe an oral medication called Clomid, also known as Clomiphene Citrate, to stimulate the pituitary gland to increase production of the hormones that manufacture testosterone.
Clomiphene citrate makes swimmers stronger
Even if a man has a normal sperm count, he might still have fertility issues if the sperm have what doctors call poor motility, or a reduced ability to travel to the egg. Medications, alcohol abuse, nutritional deficiencies, hormone issues, and genetic defects are some of the known culprits.
Fertility experts believe Clomid can boost the ability of sperm to complete their journey from ejaculation to fertilization.
The effects of Clomid male infertility treatments
Clomid male infertility treatments involve taking a pill once a day for about 3 to 6 months. If it's being used to boost sperm production, the goal will be to reach 20 million or more happily-moving swimmers per ejaculation. Conventional medical thought is that if Clomid doesn't stimulate sperm production within a few months, it is probably not the right treatment for that patient.
Once you start taking Clomid, your doctor will order regular semen analysis to find out if the drug is effective. Some health care professionals may also order testosterone tests to see if this vital fertility hormone is being stimulated.
Like many medical options, Clomid can cause side effects including temporary blurred vision, weight gain, or breast tenderness. There's another possible side effect that can be rather embarrassing for men: breast enlargement. Talk to your doctor about the potential for all Clomid side effects.
How Clomiphene Citrate Works in Men?
When men are given Clomid, it blocks the action of estrogen on the pituitary gland, causing an increase in the FSH and LH hormone levels. Higher levels of FSH and LH will boost testosterone production in men, which may improve sperm counts.
If your sperm count is low, Dr Gehlbach may order blood tests to determine if you are a candidate for treatment with Clomid. Usually, the tests will include measurements of FSH, LH, and testosterone levels.
Clomid is an inexpensive option to help improve sperm counts and testosterone levels with relatively few side effects. Some patients experience hot flashes, nausea, dizziness, headaches and temporarily blurred vision. Let Dr. Gehlbach know if you have any unusual symptoms while taking Clomid.
Men who are taking Clomid must take the medication on a daily basis because new sperm is produced every day. The typical dose is one-half a tablet per day, or 25mg of Clomid. While on Clomid, we will regularly check hormone levels to confirm an adequate response to the medication. The dose of Clomid can be custom tailored to the man's specific needs based upon the lab results. As with any other medicine, it will take time, usually several months, to determine if Clomid is having a beneficial effect on the sperm count.
To understand how clomiphene works, you need to know how the pituitary controls the making of testosterone in the testis. Testosterone is made by Leydig cells in the testis, which I explained in my last post. The pituitary releases a hormone called luteinizing hormone ("LH") that stimulates the Leydig cells to make testosterone. Testosterone is converted to the female hormone estrogen, (which I also explained in my last post,) and estrogen tells the pituitary to stop making more LH. This kind of negative feedback system is common when it comes to how hormones work. It's just like a thermostat and heater. As the room gets warmer, the thermostat sends less electricity to the heater. When the room gets colder, the thermostat sends more electricity to the heater.
Clomiphene works by blocking estrogen at the pituitary. The pituitary sees less estrogen, and makes more LH. More LH means that the Leydig cells in the testis make more testosterone.
As I explained in my last post, giving testosterone to a man does just the opposite. The pituitary thinks that the testis is making plenty of testosterone, and LH falls. As a result, the testis stops making testosterone, and the usually high levels of testosterone in the testis fall to the lower level in the blood.
So clomiphene is a way to increase testosterone in the blood and the testis at the same time. It preserves testis size and function while increasing blood testosterone.
Does Clomiphene citrate for men work?
Overall, the success rate for treating male infertility with drugs is lower than the success rate for women. For example, experts expect about 20-25% of men on fertility drugs to fertilize their partner. One study found that a combination of Clomid male infertility treatments and the antioxidant vitamin E boosted sperm count and mobility. And, ultimately, 37% of the partners of the men who took the combination became pregnant, while only 13% of partners with men taking a placebo became pregnant.
Ultimately, the only way to know for sure if Clomid is your fertility solution is to talk to a reproductive specialist. Clomid male infertility treatments may be just what your body needs to start down the path toward conception.
Clomid Success Rates for Male Infertility Treatment
Success can be defined in two different ways: improvement in sperm health and testosterone levels, and in pregnancy rates.
What kind of pregnancy rate can you expect? Your personal situation will depend not only on your fertility, but also your partner's fertility.
In studies including only couples facing male infertility, pregnancy rates after Clomid treatment vary, with some studies showing no improvement and others showing a fertility boost. The average pregnancy rate is around 13 to 15%.
A small but interesting study found that Clomid along with antioxidant treatment (like Vitamin-E) significantly raised pregnancy rates, up to 36%.
One meta-analysis looked at the results of several studies on Clomid and male infertility, specifically men experiencing idiopathic low sperm count and/or poor sperm motility.
This study found that treatment with Clomid, compared to no treatment, increased sperm concentration by about 5% and improved sperm motility by about 4%.
Reproductive hormone levels also significantly improved with Clomid treatment, with FSH levels rising 4% overall and testosterone levels rising 54%.
Perhaps the most important news for those trying to conceive, pregnancy rates doubled with Clomid treatment, when compared to those who received no treatment.
What about men experiencing azoospermia?
In one study, Clomid helped 64.3% of the men to produce sperm, with semen analysis results showing between 1 and 16 million sperm per milliliter.
For the men who did not produce sperm after Clomid treatment, all patients in this study had enough sperm to be retrieved using testicular sperm extraction. The extracted sperm could then be used for ICSI-IVF treatment.
Clomid was one of the original drugs used in post-cycle-therapy to stave off gynocomastia and raise the body's natural testosterone levels. There are some side effects involved with heavy prolonged use, such as vision problems, and there are more effective substances on the market that do the same thing, but Clomid is still an effective and inexpensive compound for any athlete's post-cycle-therapy.
For athletic purposes, Clomid does not offer a tremendous benefit to women. In men however, the elevation in both follicle stimulating hormone and (primarily) luteinizing hormone will cause natural testosterone production to increase.
This effect is especially beneficial to the athlete at the conclusion of a steroid cycle when endogenous testosterone levels are depressed. If endogenous testosterone levels are not brought beck to normal, a dramatic loss in size and strength is likely to occur once the anabolics have been removed.
This is due to the fact that without testosterone (or other androgens), the catabolic hormone cortisol becomes the dominant force affecting muscle protein synthesis (quickly bringing about a catabolic metabolism). Often referred to as the post-steroid crash, it can quickly eat up much of your newly acquired muscle.
Clomid can play a crucial role in preventing this crash in athletic performance. As for women, the only real use for Clomid is the possible management of endogenous estrogen levels near contest time. This can increase fat loss and muscularity, particularly in female trouble areas such as this hips and thighs. Clomid however often produces troubling side effects in women (discussed below), and is likewise not in very high demand among this group of athletes.
Clomid and HCG are also occasionally used periodically during a steroid cycle, in an effort to prevent natural testosterone levels from diminishing. In many instances this practice can prove difficult however, especially when using strong androgens for longer periods of time.
|Product Name||Clomiphene Citrate for men clomid male infertility treatment male hormone replacement therapy|
|Place of Origin||China legit steroid|
|Certification||ISO9001, ISO14000, KOSHER|
|Packaging Details||100grams/bag, as required|
|Delivery Time||within 48 hours after payment down, 5-8 work days for delivery|
|Payment Terms||T/T, Western union, Money gram|
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|Test Items||Specification||Test Results|
|Appearance||White or off-white powder||white powder|
|Water||Not more than 1.0%||0.38%|
|Heavy water||Not more than 0.002%||Conforms|
|Related impuries||Related compound A:Not more than 2.0%||0.86%|
|Individual:Not more than 0.5%||0.38%|
|Conclusion||This batch is complies with USP 32.|