Pramoxine HCl Local Anesthetic Drug CAS: 637-58-1 White Powder
|FOB Unit Price:||US $10 US $5|
|Purchase Qty. (g)||FOB Unit Price|
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- Model NO.: 637-58-1
- Customized: Customized
- Suitable for: Elderly, Adult
- Purity: >99%
- Molecular Weight: 329.86
- Transport Package: Disguised Package
- Origin: China
- Powder: Yes
- Certification: GMP, ISO 9001, USP, BP
- State: Solid
- Molecular Formula: C17h28clno3
- Trademark: LSW
- Specification: SGS GMP
- HS Code: 3004390090
Pramoxine Hcl Local Anesthetic Drug CAS: 637-58-1 White Powder
Synonyms: 4-(3-(p-butoxyphenoxy)propyl)-morpholinhydrochloride; Gamma-morpholinopropyl4-n-butoxyphenyletherhydrochloride; P-butoxyphenylgamma-morpholinopropyletherhydrochloride; Proctofoam;
Category: Pharmaceutical raw materials
Grade: Medical grade
Character: White powder
Usage: Muscle relaxant (smooth) and slows growth of unwanted facial hair.
Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953 and used as an antipruritic. Chemically, it is p-n butoxyphenyl gammamorpholinopropyl ether hydrochloride. During research and development, pramoxine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent.
Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in man. Like other local anesthetics, paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.
Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches. Pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations.
|Loss on drying||≤1.0%||0.12%|
|Residue on ignition||0.1%||0.04%|
|Conclusion||The results conforms with USP33|
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