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Wuhan Lianshangwang Technology Co., Ltd.

Megestrol Acetate, Norethindrone Acetate, Acting Oral Contraceptives manufacturer / supplier in China, offering Norethindrone Acetate Steroids for Acting Oral Contraceptives CAS 51-98-9, Megagrisevit Steroid Powder Clostebol Acetate for Male Bodybuilding 855-19-6, Legit Testosteron Propionate Injections (Prop 100) Injectable Steroids 100mg and so on.

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Supplier Homepage Product Anabolic Steroid Powders Norethindrone Acetate Steroids for Acting Oral Contraceptives CAS 51-98-9

Norethindrone Acetate Steroids for Acting Oral Contraceptives CAS 51-98-9

FOB Price: US $10 / g
Min. Order: 10 g
Min. Order FOB Price
10 g US $10/ g
Get Latest Price
Port: Wuhan, China
Production Capacity: 10000kg/Week
Payment Terms: L/C, T/T, Western Union, Money Gram, Bitcoin
Basic Info
  • Model NO.: 51-98-9
  • Customized: Non-Customized
  • Suitable for: Elderly, Children, Adult
  • Purity: >99%
  • Transport Package: 1kg Sterile Aluminum Foil Bag or Discreet
  • Origin: China
  • Powder: Yes
  • Certification: GMP, ISO 9001, USP, BP
  • State: Liquid
  • Trademark: LSW
  • Specification: 1kg Sterile Aluminum Foil Bag
  • HS Code: 3006920000
Product Description
99.5% Purity USP Female Steroidal Progestin Hormone Norethindrone Acetate

Pronunciation: nor-eth-IN-drone ASS-uh-TATE
Class: Progestin

 

Trade Names

 
Micronor

Pharmacology

Inhibits secretion of pituitary gonadotropins, thereby preventing follicular maturation and ovulation.

Pharmacokinetics

Absorption

Norethindrone acetate is rapidly absorbed from GI tract. T max is approximately 2 h.

Distribution

Rapid distribution of dorethindrone acetate.

Metabolism

Norethindrone is metabolized in the liver.

Elimination

Norethindrone elimination is rapid, primarily in feces.

Indications and Usage

Treatment of secondary amenorrhea; endometriosis; abnormal uterine bleeding caused by hormonal imbalance in the absence of organic pathology (eg, uterine cancer).

Contraindications

Thrombophlebitis, thrombolic disorders, cerebral apoplexy, or a history of these conditions; markedly impaired liver function or liver disease; known or suspected carcinoma of the breast; undiagnosed vaginal bleeding; missed abortion; as a diagnostic test for pregnancy.

Dosage and Administration

Secondary Amenorrhea, Abnormal UterineBleeding
Adults

PO 2.5 to 10 mg/day for 5 to 10days during second half of the theoretical menstrual cycle.

Endometriosis
Adults

PO 5 mg/day initially for 2 wk, then increase in increments of 2.5 mg/day every2wk until 15 mg/day is achieved. Therapy may be continued at this level for6 to 9 mo or until breakthrough bleeding demands temporary termination.

General Advice

  • Administer once daily, without regard to meals. Administer with food if GI upset occurs.

Storage/Stability

Store at controlled room temperature (59° to 86°F).

 

Drug Interactions

Rifampin

Elimination of norethindrone may be increased, decreasing the therapeutic effect.

Laboratory Test Interactions

Pregnanediol determinations may be altered; thyroid and LFT results may be affected; increased amounts of coagulation factors; reduced response to metyrapone test.

Adverse Reactions

Cardiovascular

Thrombophlebitis; cerebral thrombosis and embolism; hypertension; edema.

CNS

Depression; changes in libido; changes in appetite; headache; nervousness; dizziness; fatigue.

Dermatologic

Allergic rash; melasma; chloasma; hirsutism; alopecia; erythema multiforme; erythema nodosum; hemorrhagic eruption; itching.

EENT

Neuro-ocular lesions (eg, retinal thrombosis, optic neuritis).

Genitourinary

Breakthrough bleeding; spotting; amenorrhea; increased cervical erosion and secretion; cystitis.

Hepatic

Cholestatic jaundice.

Metabolic

Weight gain and loss.

Respiratory

Pulmonary embolism.

Miscellaneous

Premenstrual syndrome; backache.

 

Precautions

Pregnancy

Category X .

Lactation

Excreted in breast milk.

Children

Safety and efficacy not established.

Fluid retention

Use with careful observation when conditions that might be affected by fluid retention are present (eg, asthma, cardiac or renal dysfunction, epilepsy).

Mental depression

Carefully observe patients with history of depression.

Ophthalmic effects

Discontinue therapy if there are any sudden changes in vision or onset of proptosis, diplopia, migraine, papilledema, or retinal vascular lesions.

Patient Information

  • Instruct patient to take once daily as prescribed.
  • Advise patient that medication can be taken without regard to meals, but to take with food if GI upset occurs.
  • Warn women of childbearing potential of significant risks associated with taking this medication and becoming pregnant.
  • Instruct diabetic patient to monitor blood glucose more frequently when drug is started or dose is changed and to inform health care provider of significant changes in readings.
  • Instruct patient to report the following symptoms to health care provider: pain in groin or calves; sharp chest pain or sudden shortness of breath; abnormal vaginal bleeding; sudden severe headache or migraine headache; vision problems; yellowing of skin or eyes; or depression.
CAS 595-33-5
 
 
1 . Brief Introduction :
 

Norethindrone Acetate

Pronunciation: nor-eth-IN-drone ASS-uh-TATE
Class: Progestin

 

Trade Names

 

Aygestin
- Tablets 5 mg

Micronor (Canada)

Pharmacology

Inhibits secretion of pituitary gonadotropins, thereby preventing follicular maturation and ovulation.

Pharmacokinetics

Absorption

Norethindrone acetate is rapidly absorbed from GI tract. T max is approximately 2 h.

Distribution

Rapid distribution of dorethindrone acetate.

Metabolism

Norethindrone is metabolized in the liver.

Elimination

Norethindrone elimination is rapid, primarily in feces.

Indications and Usage

Treatment of secondary amenorrhea; endometriosis; abnormal uterine bleeding caused by hormonal imbalance in the absence of organic pathology (eg, uterine cancer).

Contraindications

Thrombophlebitis, thrombolic disorders, cerebral apoplexy, or a history of these conditions; markedly impaired liver function or liver disease; known or suspected carcinoma of the breast; undiagnosed vaginal bleeding; missed abortion; as a diagnostic test for pregnancy.

Dosage and Administration

Secondary Amenorrhea, Abnormal UterineBleeding
Adults

PO 2.5 to 10 mg/day for 5 to 10days during second half of the theoretical menstrual cycle.

Endometriosis
Adults

PO 5 mg/day initially for 2 wk, then increase in increments of 2.5 mg/day every2wk until 15 mg/day is achieved. Therapy may be continued at this level for6 to 9 mo or until breakthrough bleeding demands temporary termination.

General Advice

  • Administer once daily, without regard to meals. Administer with food if GI upset occurs.

Storage/Stability

Store at controlled room temperature (59° to 86°F).

 

Drug Interactions

Rifampin

Elimination of norethindrone may be increased, decreasing the therapeutic effect.

Laboratory Test Interactions

Pregnanediol determinations may be altered; thyroid and LFT results may be affected; increased amounts of coagulation factors; reduced response to metyrapone test.

Adverse Reactions

Cardiovascular

Thrombophlebitis; cerebral thrombosis and embolism; hypertension; edema.

CNS

Depression; changes in libido; changes in appetite; headache; nervousness; dizziness; fatigue.

Dermatologic

Allergic rash; melasma; chloasma; hirsutism; alopecia; erythema multiforme; erythema nodosum; hemorrhagic eruption; itching.

EENT

Neuro-ocular lesions (eg, retinal thrombosis, optic neuritis).

Genitourinary

Breakthrough bleeding; spotting; amenorrhea; increased cervical erosion and secretion; cystitis.

Hepatic

Cholestatic jaundice.

Metabolic

Weight gain and loss.

Respiratory

Pulmonary embolism.

Miscellaneous

Premenstrual syndrome; backache.

 

Precautions

Pregnancy

Category X .

Lactation

Excreted in breast milk.

Children

Safety and efficacy not established.

Fluid retention

Use with careful observation when conditions that might be affected by fluid retention are present (eg, asthma, cardiac or renal dysfunction, epilepsy).

Mental depression

Carefully observe patients with history of depression.

Ophthalmic effects

Discontinue therapy if there are any sudden changes in vision or onset of proptosis, diplopia, migraine, papilledema, or retinal vascular lesions.

Patient Information

  • Instruct patient to take once daily as prescribed.
  • Advise patient that medication can be taken without regard to meals, but to take with food if GI upset occurs.
  • Warn women of childbearing potential of significant risks associated with taking this medication and becoming pregnant.
  • Instruct diabetic patient to monitor blood glucose more frequently when drug is started or dose is changed and to inform health care provider of significant changes in readings.
  • Instruct patient to report the following symptoms to health care provider: pain in groin or calves; sharp chest pain or sudden shortness of breath; abnormal vaginal bleeding; sudden severe headache or migraine headache; vision problems; yellowing of skin or eyes; or depression.
 
 
3 . Application :
 
Mainly used for short-acting oral contraceptives, also can be used for intramuscular injection of long-acting contraceptives.
For the treatment of dysmenorrhea, amenorrhea, dysfunctional uterine bleeding, endometriosis and endometrial adenocarcinoma
 
4 . Three Focus you may care about :
 
a. We have experience in this area, In order to smooth clearance of goods, we provide a variety of packaging.
b. We are a professional team, have Special way to ship 100 grams to 100kg powders at one time to your country.
c. We have Adequate stock , and can arranged within 24hours when receive the payment.Tracking number would be informed quickly after shipment.
 
 
5 . Additional information :
 

MOQ

10grams

Price

Negotiable

Shipping

Fast and secure shipping by DHL,EMS,UPS,TNT, FedEx.

Packaging Details

1kg/foil bag or as required

Lead time

Within 12 hours after receiving the payment

Payment Terms

Western Union, MoneyGram, T/T ,Wire transfer

Supply Ability

500-1000kg/month

 
 
6 . Our professional team :
 
We are a professional team.so We don't just do a one time business ,our colleagues have devoted themselves to our cunstomers for years.NO FAKE,NO CHEAT.
I Rich experience
Our company, specialize in this field for many years, our steroids and hormones exported to Overseas, to Europe,Africa,Asia, Americas and other country.Customers thinking highly of our exclusive service.
II Great quality, purity and favourable
Good quality is one of our secret success, our high quality steroid's purity reached to 99.5% enough.Welcome order the samples, our MOQ is 10grams.
III Safest and fastest delivery
a.We have Adequate stock,and can arranged within 24hours when receive the payment.Tracking number would be informed quickly after shipment.
b.We have special way could ship 0.01 kilo to 50 kilo products a time. We offer melting powder into liquid service
IV Good after-sales service
24/7 is available, tell the package update asap, and will try best solve when customer encountered various problems!
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