99% Sarms Raw Powder Ostarine / Mk-2866 / Mk2866 Enobosarm CAS 841205-47-8 for Bulking and Cutting Cycle
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- Model NO.: CAS 841205-47-8
- Specification: USP
- HS Code: 8888
- Trademark: LSW
- Origin: China
What is Ostarine?
Ostarine (MK-2866) is a SARM developed by GTx for the prevention and treatment of muscle wasting.
It may eventually be a medical prescription for the prevention of cachexia, atrophy and sarcopenia as well as for Hormone or Testosterone Replacement Therapy.
As a research chemical, Ostarine belongs to a class of chemicals know as SARMS or selective androgen receptor modulators. SARMS create selective anabolic activity at certain androgen receptors. In comparison to testosterone and other anabolic steroids, the advantage of SARMS, is they do not have androgenic activity in non-skeletal muscle tissues. Ostarine is effective in maintaining
and increasing lean body mass.
HOW Ostarine (MK-2866) WORKS?
Ostarine (MK-2866) binds to the androgen receptors just like anabolic steroids do, but it does this
selectively, which means that it has considerably less side effects.
A 12 week double blind placebo controlled phase II clinical trial was conducted on ostarine, which showed that ostarine increased lean muscle mass and improved physical function without the negative side effects seen with testosterone or other anabolic steroids.
Ostarine (MK-2866) was developed mainly for the treatment of muscle wasting and osteoporosis.
Nonetheless, it also retains nitrogen and strengthens the joints. Therefore, it is a very versatile compound in matters of health benefits.
Lean muscle gains (bulking)
Ostarine (MK-2866) is the most anabolic of any SARMS, making its first and foremost use for wanting
to gain lean muscle. The gains in total weight will not be comparable to bulking steroids, however the
total gains will almost entirely be lean muscle.
The gains that are made on ostarine are very keepable and users generally see an increase of up to 7 lbs. of lean body mass over and 8 week cycle at 25mg day (diet dependent). The most common dosage is 25 mg for 8 weeks. The side effects that one encounters with steroid use will not be present on cycle.
Generally, with ostarine, the higher the dosage, the more suppression. Although suppression is minimal and is nowhere comparable to suppression that one encounters on steroids, any cycle of ostarine over a 4 weeks period requires a 3 week mini pct. A serm is not required in this pct.
Losing Bodyfat (cutting)
Ostarine would primarily fit into a cutting protocol for the maintenance of muscle mass while reducing calories.
As Ostarine has anabolic effects, the dieter can cut calories without having to worry about muscle or strength loss.
Ostarine has also shown noticeable nutrient partitioning effects among users, another reason why it can be of great help when cutting.
A 15-20 mg dosing protocol for 6-8 weeks is good for cutting with Ostarine without undergoing any side
effects or high suppression. However it must be stated that due to the lack of androgenicity, muscle hardness and overall results are not as prominent as with the SARM S-4.
Recomping is where ostarine truly shines. The recomping effect of losing fat and gaining muscle at the same time is what the majority of users are looking for. Trying to achieve this when you are not absolutely new to training is extremely difficult.
Where Ostarine shines for recomping is in its nutrient partitioning benefits. Calories are taken from fat stores and calorie intake is fed to the muscle tissue.
The dosing protocol of 20-25mg for 6-8 weeks will give excellent recomp effects.
The effects of ostarine translate to anabolism in bone and skeletal muscle tissue, which means it could be used in the future for a variety of uses, such as osteoporosis and as a concurrent treatment with drugs that reduce bone density. Therefore it has great application as a compound to use for rehabilitation of injuries, in particular bone and tendon related injuries.
Doses of 12.5mg per day is recommend for such purposes and improvement in joint movement that can be seen after just 6-8 days.
Depending on the objectives, there are a few ways to stack Ostarine:
Endurance: You can stack ostarine with cardarine for increased endurance before your workout or run.
Anabolic steroid stack: Ostarine can be added to your existing anabolic steroid cycle in order to
increase lean muscle mass and strength without additional side effects.
During PCT or bridge: Ostarine is minimally suppressive at 25mg per day for 4 weeks or less. Thus, it can be stacked into your post cycle therapy, or your bridging phase, to maintain strength and muscle.
SARMs triple stack: If you want to recomp (build muscle mass while losing fat at the same time), Ostarine stacks beautifully with andarine and cardarine.
HALF LIFE, USE AND DOSAGE
Ostarine's half life is a very robust 24 hours, so only once a day dosage is necessary.
The liquid form should be shaken, squirted into the mouth, and swallowed immediately. It is also recommended to chase down with some juice or water. Furthermore, it is important NOT to hold ostarine under tongue or mix the liquid in a cup, as it can be lost.
Ostarine (MK-2866) dosage is typically between 12.5-50mg per day. The lower end dosages are
for those who want to use it for its healing abilities, and the higher end dosages are for more recomping and muscle mass gain.
MK 2866 carries a half-life of approximately 24 hours.
Effects of Ostarine
Ostarine can be used for gaining as well as preserving muscle mass. For the athlete, this means it can be used in both cutting and bulking phases. The user can expect significant gains in lean body mass without unwanted water retention or fear of gynecomastia often associated with anabolic steroids. The individual will unlikely gain as much weight as he would from a cycle of Dianabol or Anadrol; however, the gains will be cleaner and easier to maintain post use. It is very common for the individual to associate all weight gain with positive gains when using certain steroids, but lean muscle gains are the only ones that
Ostarine can also be very useful during the cutting or dieting phase. This may be the best time to use the SARM for its muscle protecting qualities. In order to lose body fat, you must burn more calories than you consume. Being in a calorie deficit puts lean muscle mass at risk, some loss will occur. If we can protect our muscle mass during a diet, we not only look better we actually continue to burn fat. A loss of muscle mass will hinder the metabolism making fat loss difficult. Protect the muscle mass and you protect the metabolism. Ostarine will also offer up significant joint healing and repair, which is invaluable when dieting. Harsh or hard dieting can often lead to joint discomfort. If we can protect our joints, as well as increase tendon and ligament strength, collagen synthesis and enhance bone mineral content, we can continue to train and train harder. The effects of MK 2866 in this manner are truly beneficial in a bulking or cutting phase, but they will typically stand out more during the cutting phase. The effects of Ostarine in this regard are so strong data has shown it may directly treat injuries, and not a masking scenario as with pain meds but actual healing of joints, ligaments, tendons and bone.
Side Effects of Ostarine:
The side effects of Ostarine are limited as it appears to be a relatively side effect friendly drug. Many of
the adverse effects associated with anabolic steroids will not exist with this SARM; however, some will, although mildly.
Estrogenic: The side effects of Ostarine should not include those of an estrogenic nature as the SARM
does not aromatize. There is no conversion of testosterone to estrogen associated with this drug.
Water retention, bloating, gynecomastia or high blood pressure due to water retention cannot occur.
However, data shows that some increases in existing estrogen may occur, but should be very mild and
not enough to warrant the use of an anti-estrogen. If this very slight increase is concerning, if an anti-estrogen is used, you may easily bottom out your estrogen levels, which can lead to numerous hormone imbalances and related effects.
Androgenic: Androgenic side effects of Ostarine, despite directly affecting the androgen receptor
should not exist. This compound does not convert to DHT; acne and hair loss cannot occur. Androgenic side effects associated with virilization in women are also impossible. As there is no direct androgenic
activity related to DHT, prostate issues should also be non-existent.
Cardiovascular: The side effects of Ostarine should present minimal cardiovascular risk. Both HDL and LDL levels may be reduced, but all data shows minimal to insignificant reductions.
Testosterone Suppression: It's often said SARM's will not suppress natural testosterone production, and it's true they will not compared to anabolic steroids. However, some suppression is possible, but
complete suppression is not. A testosterone-boosting supplement may be warranted while using MK 2866. Post Cycle Therapy (PCT) data is somewhat inconclusive as to if this is needed. Some men seem to experience greater levels of testosterone
suppression than others.
Hepatotoxicity: Although orally administered, the side effects of Ostarine do not include liver toxicity.
MK 2866 does not belong to the C17-alpha alkylated (C17-aa) class of drugs like many oral anabolic
steroids. It does not mirror the MI metabolite associated with the SARM S4 that gives that particular
SARM some hepatic activity.
MK 2866 is an orally administered SARM. For the purposes of muscle preservation when dieting, a minimum of 15mg per day is normally taking. For growth to be spurred, most users will find 20-25mg per day
to be a good place to start. Some heavier individuals may find 30mg per day to be needed, but most
data shows such doses often make little difference compared to the 20-25mg ranges in most men.
Total use will normally last 6-8 weeks with 4 weeks of no SARM use once a cycle of Ostarine is
complete. Although testosterone suppression may not be heavy, PCT may or may not be needed.
However, some suppression will exist and it's best to give the body a chance to normalize. MK 2866
carries a half-life of approximately 24 hours; once daily dosing is sufficient. There is no advantage
to multiple doses per day.
Availability of MK Ostarine
Ostarine is widely available and can be found through most online research chemical companies that offer ancillaries, peptides and other non-steroidal and non-controlled substance labeled medications. Pricing will vary depending on numerous factors, which
include manufacturer, dosing strength, liquid or capsule. True SARM's like MK 2866 will normally be
found through research chemical companies.
MK 2866 is an effective medication for providing a significant anabolic boost. The personal reviews of many individuals online are mixed with most negative reviews appearing to be based on misunderstanding. This SARM is not going to pack on 30lbs of weight in a matter of weeks like the steroid Anadrol will, and it's not going to provide a level of hardness comparable to a Trenbolone and Masteron combination. In order to appreciate any medication used for anabolic purposes, we have to first understand what it's capable of and what it's not. Ostarine can be a solid alternative over anabolic steroids, a good bridge between steroid cycles (assuming you're not concerned with full natural hormone recovery at that time), or a good addition to a total stack of other items. You must also consider where you're getting the
product. Most purchases will be made from research chemical companies, and there are some that
manufacturer inferior product. However, with numerous high quality labs on the market, most of the poor ones rarely stay in business very long.
By now most of you will have heard of SARMS, or selective androgen receptor modulators, these new and pioneering supplements bind to the androgen receptor in pretty much the same way anabolic steroids such as Testosterone would, but in a novel and selective way. They exert many of the same anabolic
effects that steroids do, but without many of the sides associated with other androgens. The Androgen
Receptor plays a vital and significant role in the development and function of sexual organs, skeletal
muscle, and bone, as well as other human organs. When Selective Androgen Receptor Modulators bind to the receptor, they demonstrate powerful anabolic activity in both muscle and bone. This is because
they bind to the receptor and change its action in a novel way that is significantly different than typical
androgen receptors stimulators, such as synthetic androgens and non-synthetic androgens (Steroids).
Therefore, they are able to alter the gene-transcription process in a manner that is tissue specific,
in this particular case we are interested in its effects on bone and muscle.
Ostarine exerts its effects in a very anabolic way, comparisons have been made with the Anabolic steroid primobolan. Generally, a user will see increased muscle mass, very positive effect on joints and bones, as well as as boost in nitrogen retention.
In comparison, most steroidal androgens (steroids) convert to DHT or Estrogen so you have the increased chance of DHT related side effects: enlarged prostate for one, and hair loss if your prone, as well as a whole list of other potential DHT related side effects. Estrogen causes a whole host of problems too: Water retention (Edema), Hypertension (High blood pressure) and the unwelcomed and, often hard to
treat, enlargement of the male breast tissue (gynecomastia - gyno)(2). You also get your own testosterone production shutdown on cycle, so a Post cycle therapy protocol
is essential to restore correct testosterone levels. If proper pct is not followed after a cycle, the ongoing effects of impotence can be seen for many months without full testosterone recovery. However, those
problems along with many others, if the steroid of choice is a progestin, can, to some degree, be
eradicated through science, and the development of these new SARMS.
Ostarine (MK-2866) doesn't convert to DHT or display any of the side effects by Dihydrotestosterone.
In blood tests, a slight raise in estrogen levels can be seen, and that might be one of the key factors in its tremendous potential for treating tendon, ligament, and bone injuries or illnesses. It also displays a
very anabolic effect on muscle tissue, causing considerable and easy to maintain gains in muscle over
4-6 weeks, with little to no sides and no real PCT is needed afterwards.
Another interesting aspect, as opposed to your typical steroid, is that SARMS remain very hard to
detect for anti-doping agencies. Since SARMS bypass the well known 4 ring steroid structure, they are not steroids.
However, SARMS exert many of the same performance enhancing effects that steroids do, without the side effects (3)
Ostarine: Unleashing its power
The big question is, how do you get the most bang for your buck from Ostarine (MK-2866)?
First, we need to get some facts straight on what it is exactly, its half life and best dose. Ostarine has a
half life of 23.8 hours, so a once a day dose is the most effective to get your biggest peak of blood
plasma serum levels. Depending on your goals though, there are a couple of dosage protocols I personally recommend.
Dosing at 25mg-36mg a day gave me my biggest gains in muscle and the best muscle pumps over a 4
week period. Dosages higher than 36mg did not increase the gains in lbm or strength over the same
period; for someone weighing 200lbs 25mg is enough to elicit very good anabolism. However, in
experiments I carried, for someone weighing above 210-20lbs, 36mg out seemed to be a much better dose and offer better general lbm gain. With this dose
muscle hardness can be seen to increase after about 6 days.
I suggest front loading Ostarine the first week, close to 50% your intended dose, this will speed up the
saturation of ostarine in the system and its affect on the androgen receptor.
These very same doses can be used on a cut and maintain muscle mass, with decreased calories.
I highly recommend the use of Ostarine in cutting (dieting), as even in a calorie surplus diet fat loss can seen at quite a high rate of 1-2lb a week. On a cut, with added help of Cardarine (GW-501516), the
loss of visceral fat can be increased exponential. Muscle tone and hardness will also increase at a rapid rate revealing a ripped and cut physique. You'll also be in a lot better state, health wise, than if steroids were used to increase muscle retention during the same period of time.
Bone and tendon repair dosing:
One of the outstanding facets of Ostarine (MK-2866) is that it doesn't just build muscle, it increases
tendon strength, improves the health of the ligaments, increases bone density and increases the rate at which collagen is turned over. To achieve this, a dose of 12mg ed is adequate. In addition, this dose
promotes improvement in joint movement that can be seen after just 6-8 days. This dose is very
effective for treating injuries like shin splints, and can be used post operation to help maintain muscle
and speed up the recovery of the limb, (Bone/Tendon) that has been operated on.
Supplementation while using SARMS:
My favorite supplements which seem to increase the effectiveness of Ostarine is Creatine. By itself, Creatine increases igf-1 levels, bone density, lean body mass, and prevents the release of homocysteine,
thus preventing cardiovascular problems. Zinc and magnesium are a must as both are vital for increase in testosterone levels, androgen receptor sensitivity, and igf-1 levels to remain at a maximal level.
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