USP Peptides Aod 9604 CAS 221231-10-3 Fragment 177-191 for Bodybuilding
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|FOB Unit Price:||US $1 US $0.9 US $0.8 US $0.7 US $0.6|
|Purchase Qty. (vials)||FOB Unit Price|
|Production Capacity:||Mass Stock|
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- Model NO.: 221231-10-3
- Customized: Customized
- Suitable for: Elderly, Children, Adult
- Purity: >99%
- MW: 1815.1
- MOQ: 10 Vials
- Trademark: LSW
- Origin: China
- Powder: Yes
- Certification: ISO 9001, USP, BP
- State: Solid
- Mf: C78h123n23o23s2
- Appearance: White Powder
- Deliver Time: Within 24 Hours
- Specification: USP, ISO9001
- HS Code: 1111111111
AOD9604 is based on a small part of the human growth hormone molecule. This hormone, which occurs naturally in the body and which stimulates fat metabolism, is suppressed in obese people.
|Product name:||AOD 9604;Fragment 177-191|
|Molecular Mass:||1815.08 Da (g/mol)|
|Storage:||Closed, below 2 ~ 8°C preservation|
|Amino Acid Sequence:||Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe|
AOD9604 is a peptide (a chain of amino acids) which was developed and patented by a company called Metabolic Pharmaceuticals in Australia in the late 1990s. AOD stands for "Anti Obesity Drug". This peptide has an amino acid sequence that mimics the lipolytic region of human growth hormone (the region of this hormone thought to be responsible for burning fat) and it has been promoted variously as a weight loss supplement, as an aid to muscle and cartilage repair, and a treatment for osteoarthritis by its manufacturers. It is also known as lipotropin and Tyr-hGH fragment, and is generally available these days as a transdermal cream or an injectable.
AOD9604 is an analog of the GRF which signals the effects of growth hormone. It is a 15-mer peptide residue of the C-terminus of HGH to which tyrosine is added at the N-terminal end. This synthetically produced hormone is very common to weightlifters and bodybuilders because of a number of physical benefits. Studies claimed that it actually acts on the reduction of excessive adipose tissues such as those in the abdominal area, increase in muscle mass, and enhances the lipid content of the body.
Obesity is the Western World's most common health problem, and has reached epidemic proportions according to the World Health Organisation. More than 20% of the adult population in developed countries are obese - more than 300 million adults worldwide. In addition, more than 50% of adults in developed countries are overweight. Obesity is associated with other health-related problems such as heart disease, cancer and diabetes.
AOD9604 is a polypeptide (177-191) of the C-terminus of Human Growth Hormone (hGH) with a N-terminal tyrosine end.
AOD9604 contains a lipolytic domain that may be responsible for the lipolytic action of hGH. AOD9401 induced lipolysis, antilipogenesis and fat oxidation in adipose tissue in vitro. In vivo, AOD9401 induced weight loss without affecting food intake as well as increasing lipolytic sensitivity and increasing fat oxidation with no adverse effects on insulin sensitivity.
AOD9604 has also been studied for its metabolic actions in obese Zucker rats. Daily treatment with an oral dose of AOD9604 of 500 mg/kg body weight for 19 days reduced over 50% body weight in comparison with the control. The adipose tissues of the AOD9604 treated animals were found to have an increase in lipolytic activity. In contrast to chronic treatment with intact hGH, chronic treatment with AOD9604 showed no adverse effect on insulin sensitivity of the animals, as demonstrated with euglycemic clamp techniques
The drug - codenamed AOD9604 - was taken orally once daily by 300 obese patients at five trial sites over a 12-week period. Six doses were used - 0 mg (placebo), 1mg, 5 mg, 10 mg, 20 mg and 30 mg.
Specific dosage, according to the degree of obesity, meanwhile, had better consult your doctor.
|Appearance||White to off white powder||Consistent|
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