Antifungal Drug Voriconazole CAS: 137234-62-9 White Powder
|FOB Unit Price:||US $5 US $3|
|Purchase Qty. (g)||FOB Unit Price|
|Port:||Hong Kong, Hong Kong|
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- Model NO.: 137234-62-9
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- MW: 349.31
- Transport Package: Discreet Package
- Origin: China
- Powder: Yes
- Certification: GMP, ISO 9001, USP
- State: Solid
- Mf: C16h14f3n5o
- Trademark: LSW
- Specification: USP, BP
- HS Code: 2906131000
Chemical name: VORICONAZOLE
Appearance: White powder
Usage: antifungal drug
|CAS No.||137234-62-9||Outer Packing||1KG|
|Production date||2016.04.04||Shelf life||2018.04.03|
|Items of analysis||Specification||Results|
|Appearance||White or almost white crystalline powder||white crystalline powder|
|Voriconazole Relatated Compound B||≤0.2%||ND|
|Voriconazole Relatated Compound F||≤0.1%||ND|
|Residue on ignition||≤0.1%||0.06%|
Voriconazole (vor" i kon' a zole) is a synthetic triazole and a derivative of fluconazole, which is believed to act through inhibition of the fungal 14α-ergosterol demethylase that is responsible for converting lanosterol to ergosterol, which blocks cell membrane synthesis. Voriconazole has a broad spectrum of activity particularly against candida and aspergillus. Voriconazole was approved for use in the United States in 2002. Current indications include treatment of invasive aspergillosis, esophageal candidiasis and serious candidal infections. It is also used as empiric antifungal therapy in patients with neutropenia and persistent fever as well as preventive antifungal therapy in high risk individuals. Voriconazole is available as tablets of 50 and 200 mg, in an oral suspension (40 mg/mL) and in a parenteral formulation generically and under the brand name Vfend. Serious fungal infections are typically treated initially with intravenous voriconazole (4 to 6 mg/kg every 12 hours) for 3 to 10 days, followed by more prolonged therapy with oral forms (20 mg every 12 hours). Common side effects include nausea, photosensitivity, hallucinations, headache, visual disturbances and rash.
Voriconazole is used to treat invasive aspergillosis andcandidiasis and fungal infections caused by Scedosporium and Fusarium species, which may occur in immunocompromised patients, including people undergoing allogeneic bone marrow transplant (BMT), who have hematologic cancers or who undergo organ transplants.
It is also used to prevent fungal infection in people as they undergo BMT.
It is also the recommended treatment for the CNS fungal infections transmitted by epidural injection of contaminated steroids.
It can be taken by mouth or given in a doctor's office or clinic by intravenous infusion.
Do NOT use voriconazole if:
you are allergic to any ingredient in voriconazole
you have untreated low blood calcium, magnesium, or potassium levels
you are taking astemizole, a barbiturate (eg, phenobarbital), carbamazepine, cisapride, an ergot alkaloid (eg, dihydroergotamine, ergotamine), everolimus, fluconazole, pimozide, quinidine, rifabutin, rifampin, sirolimus, St. John's wort, or terfenadine
Contact your doctor or health care provider right away if any of these apply to you.
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