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GLP-1 (7-37), CAS 106612-94-6), Polypeptide manufacturer / supplier in China, offering Polypeptide GLP-1 (7-37) Acetate for Diabetes Mellitus Treatment, Sell 1-Testoster Muscle Mass CAS 65-06-5, Methyltrienolon / Metribolon Cutting Cycle Steroids Male Bodybuilder and so on.

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Supplier Homepage Product Peptide And Human Growth Hormone Supplements Polypeptide GLP-1 (7-37) Acetate for Diabetes Mellitus Treatment

Polypeptide GLP-1 (7-37) Acetate for Diabetes Mellitus Treatment

FOB Price: US $1 / g
Min. Order: 100 g
Min. Order FOB Price
100 g US $1/ g
Get Latest Price
Production Capacity: Mass in Stock
Transport Package: 1 Kg/ Aluminum Foil Bag, 25kgs/ Drum
Payment Terms: T/T, Western Union, Money Gram
Basic Info
  • Model NO.: 1045-69-8
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • Appearance: White Powder
  • MW: 3355.74
  • Trademark: LSW
  • Origin: China
  • Powder: Yes
  • Certification: ISO 9001, USP
  • State: Solid
  • Einecs No: 106612-94-6
  • Mf: C151h228n40o47
  • Storage: Shading, Confined Preservation
  • Specification: USP
  • HS Code: 2801100000
Product Description
99% Polypeptide Hormones GLP-1 (7-37) Acetate
CAS 106612-94-6 Glucagon-Relatedpeptide 1 for The Diabetes Mellitus Treatment 
 
Description
Glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a gut hormone. The biologically active forms of GLP-1 are:GLP-1-(7-37) and GLP-1-(7-36)NH2. 
 
GLP-1 secretion by L cells is dependent on the presence of nutrients in the lumen of the small intestine. The secretagogues (agents that cause or stimulate secretion) of this hormone include major nutrients like carbohydrate, protein and lipid. Once in the circulation, GLP-1 has a half life of less than 2 minutes, due to rapid degradation by the enzyme dipeptidyl peptidase-4. 
 
GLP-1 (7-37) is a truncated, bioactive form of GLP-1 that is the product of proglucagon 
processing in intestinal endocrine L cells. It is a potent insulinotropic hormone. 
 
 
Specification
GLP-1 (7-37) Acetate
Sequence:His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Alias : 7-37-Glucagon-likepeptide I (human);Glucagon-relatedpeptide 1 (Rana catesbeiana),3-L-glutamicacid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-31-glycine-32-de-L-lysine-
Cas No.: 106612-94-6
Molecular Formula: C151H228N40O47
Molecular Weight: 3355.74
Purity (HPLC): 99.0%
Appearance: White powder
Single Impurity (HPLC): 1.0%
Amino Acid Composition: 10% of theoretical
Peptide Content (N%): 80% (by %N)
Water Content (Karl Fischer): 6.0%
Acetate Content (HPIC): 15.0%
Grade : Pharmaceutical Grade
Storage: Closed, below 2 ~ 8ºC preservation 
Usage : GLP-1 can obviously improve the blood glucose in type 2 diabetes animal models or patients through a variety of mechanisms, which promote the regeneration and repair of islet beta cells, increase the number of beta cells is particularly significant role, provides a very good prospect for the treatment of type 2 diabetes mellitus.
 
 
Application
Effect of GLP-1 GLP-1 can protect beta cells can act on the pancreatic beta cells, promote the synthesis of insulin, insulin gene transcription and secretion and can stimulate the proliferation and differentiation of islet beta cells, inhibit the apoptosis of pancreatic beta cells, increase the number of beta cell of islet [2-5]. In addition, GLP-1 also can be applied to the pancreatic alpha cells, strongly inhibit the release of glucagon, and act on the islet delta cells, promote the secretion of somatostatin, somatostatin cells and can be used as a paracrine hormone involved in the inhibition of glucagon.
 
GLP-1 with glucose concentration dependent hypoglycemic effect, i.e. only rise in glucose levels under the condition of GLP-1, only play a hypoglycemic effect, but in normal blood sugar levels, caused no further decrease. The glucose concentration dependence of the GLP-1 is its hypoglycemic properties of clinical application safety of foundation and security, thereby avoiding people may cause severe hypoglycemia in patients with existing drug treatment for diabetes and scheme of worry.
 
 
Physiological functions of GLP-1 include
GLP-1 possesses several physiological properties that make it (and its analogs) a subject of intensive investigation as a potential treatment of diabetes mellitus, The known physiological functions of  GLP-1 include: 
increases insulin secretion from the pancreas in a glucose-dependent manner. 
decreases glucagon secretion from the pancreas. 
increases beta cells mass and insulin gene expression. 
inhibits acid secretion and gastric emptying in the stomach. 
decreases food intake by increasing satiety. 
 
Commerce Clause  
Minimum order quantity2mg
PriceNegotiable
Packaging Details2mg/vial or as your request
Delivery timeWithin12 hours after receiving the payment
Payment TermsWestern Union, Money Gram, T/T, Bitcoin
ExpressFedex,DHL.TNT. EMS,Ups
Supply Ability:5000g/month
 
 
If you feel that you could benefit from GLP-1 (7-37) Acetate, or any other form of Peptides, we strongly encourage you to contact us.

Mobile: +86 18872220653
 
 
 

 
 

 
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