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Wuhan Lianshangwang Technology Co., Ltd.

Kinase Inhibitors, Treat Metastatic Non-Small Cell Lung Cance, Afatinib manufacturer / supplier in China, offering USP Kinase Inhibitors Afatinib 439081-18-2 Gilotrif for Lung Cancer Treatment, Nandrolone Phenypropionate Muscle Growth Anabolic Steroid Nand Pheny 62-90-8, Mupirocin CAS 12650-69-0 Bactroban Powder for Skin Infections Treatment and so on.

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Supplier Homepage Product Pharmaceutical Intermediates Others Pharmaceutical Intermediates USP Kinase Inhibitors Afatinib 439081-18-2 Gilotrif for Lung Cancer Treatment

USP Kinase Inhibitors Afatinib 439081-18-2 Gilotrif for Lung Cancer Treatment

Purchase Qty.:
(gram)
5-49 50-99 100-499 500-999 1,000+
FOB Unit Price: US $24 US $23 US $22 US $21 US $22
Purchase Qty. (gram) FOB Unit Price
5-49 US $24
50-99 US $23
100-499 US $22
500-999 US $21
1,000+ US $22
Get Latest Price
Port: Hong Kong, Hong Kong
Production Capacity: Mass Stock
Payment Terms: T/T, Western Union, Money Gram, Bitcoin
Basic Info
  • Model NO.: 439081-18-2
  • Customized: Non-Customized
  • Suitable for: Elderly, Children, Adult
  • Purity: >99%
  • MW: 485.944
  • MOQ: 5g
  • Transport Package: Disguised Package or as Required
  • Origin: China
  • Powder: Yes
  • Certification: HSE, ISO 9001, USP, BP
  • State: Powder
  • Mf: C24h25clfn5o3
  • Appearance: White or Nearly White Crystalline Powder
  • Trademark: LSW
  • Specification: SGS GMP
  • HS Code: 3002200000
Product Description
USP Kinase Inhibitors Afatinib 439081-18-2 Gilotrif for Lung Cancer Treatment 

1. Quick Details:
 
Product name:Afatinib (BIBW 2992);Gilotrif
Synonyms:BIBW 2992;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;Tovok;Tovok, BIBW 2992;BIBW2992 Afatinib;Afatinib (BIBW 2992);ToMtovok;(S,E)-N-(4-(3-chloro-4-fluorophenylaMino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(diMethylaMino)but-2-enaMide
CAS:439081-18-2
MF:C24H25ClFN5O3
MW:485.944
Purity:99.5% min 
Appearance:White or Nearly White Crystalline Powder
MOQ:10G
Specifications:Pharmaceutical Grade
Deliver time:About 5 days
Deliver methods:TNT,EMS,HKEMS,DHL,ect.(door to door)

2. What is Afatinib ?

Afatinib is pronounced aff-a-tin-ib. It has the brand name Giotrif (jee-oh-triff). It is a type of biological therapy called a tyrosine kinase inhibitor (TKI). It is a treatment for non small cell lung cancer that has spread outside the lung or to other parts of the body.

It has received regulatory approval for use as a treatment for non-small cell lung cancer,although there is emerging evidence to support its use in other cancers such as breast cancer.

3. How afatinib works:

This type of drug works by blocking particular proteins on cancer cells that encourage the cancer to grow. Afatinib blocks proteins called epidermal growth factor receptors (EGFR). Cancers that have these receptors are called EGFR positive.

Between 10 and 15 people out of every 100 with non small cell lung cancer (10 to 15%) have EGFR positive cancer. Doctors check your cancer cells to see if they have the receptors before you have this treatment.

Afatinib may shrink the cancer or stop it growing for a time

4. Uses and fuction:

Afatinib is used to treat a certain type of lung cancer (non-small cell lung cancer) that has spread to other parts of the body. It belongs to a class of drugs known as kinase inhibitors. It works by slowing or stopping the growth of cancer cells. It binds to a certain protein (epidermal growth factor receptor-EGFR) in some tumors.

5. Mechanism of action:

Like lapatinib and neratinib, afatinib is a protein kinase inhibitor that also irreversibly inhibits human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases. Afatinib is not only active against EGFR mutations targeted by first generation tyrosine-kinase inhibitors (TKIs) likeerlotinib or gefitinib, but also against mutations such as T790M which are not sensitive to these standard therapies.Because of its additional activity against Her2, it is being investigated for breast cancer as well as other EGFR and Her2 driven cancers.

6. COA:
 
ItemRequirementsTest Results
DescriptionOff-white powderOff-white powder
IdentificationHPLC ,NMRComplies
Residue on Ignition≤0.10%0.05%
Loss on Drying≤0.50%0.15%
Heavy Metal≤20ppm<20ppm
Purity(HPLC)≥99.0%99.99%
ConclusionIt complies with EnterpriseStandard
 
7. Our Adwantage: 

   High quality with competitive price: 
   1) Standard: Enterprise Standard
   2) All Purity:>=99%
   3) We are manufacturer and can provide high quality products with factory price. 

   Fast and safe delivery:
   1) Parcel can be sent out in 24 hours after payment. Tracking number available
   2) Secure and discreet shipment. Various transportation methods for your choice. 
   3) Customs pass rate: >=99%
   4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring. 

   We have clients throughout the world:
   1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire. 
   2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility. 
   3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

   Everybody is talking the similar words, what I want to say is: Just give me a chance, Just have a try on me, maybe you will get a surprise from me!  
 
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