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GW501516 (also known as GW-501,516, GW1516, GSK-516) is a PPAR& receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s, was entered into clinical development as a drug candidate for metabolic diseases and cardiovascular diseases, and was abandoned in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs.
In 2007 research was published showing that high doses of GW501516 given to mice dramatically improved their physical performance; the work was widely discussed in popular media, and led to a black market for the drug candidate and to its abuse by athletes as a doping agent. Product Feature
Product Name: GW501516 Other Name: Cardarine Endurobol CAS #: 317318-70-0 Purity: 99% min. Molecular Formula: C19H18F3N3O6 Molecular Weight: 453.5 Our GW501516 / Cardarine Endurobol has a purity not less than 99%. Product Specification / Models
There are two main uses with GW-501516. The first and most common use is that of increased endurance. GW has been banned for professional athletes due to the unfair advantage it provides to endurance athletes. Anyone want a drastic increase in endurance will find that GW truly shines in this aspect. It takes effect very quickly and the results can be staggering. A common dose of 10 mg day will provide a significant increase in endurance.
The second common usage with GW is that of fat loss. Many users turn to GW as it has shown to melt off fat while still being non-catabolic. You will find that you can still hold on to some muscle as you are losing fat. It helps when you are running it in conjunction with SARMS Ostarine and S4, to hold on to as much muscle as possible. A dosage of 10 mg a day will provide good amounts of fat loss, but an increase to 20 mg a day will provide much more in this area.
2.Other Information Reference List of Available SARMs:
CAS Product Name Chemical Name 159752-10-0 MK-677 Ibutamoren Mesylate 841205-47-8 MK-2866 Ostarine 401900-40-1 Andarine S-4 Andarine 1165910-22-4 LGD-4033 Anabolicum 317318-70-0 GW501516 Cardarine Endurobol 1182367-47-0 RAD140 Testolone 1370003-76-1 YK11 YK-11 1379686-30-2 SR9009 Stenabolic 2627-69-2 Aicar Acadesine
GW501516 (also known as GW-501,516, GW1516, GSK-516 and Endurobol)is a PPAR receptor. It activates the same pathways activated through exercise, including PPAR and AMP-activated protein kinase. It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease. GW501516 has a synergistic effect when combined with AICAR: the combination has been shown to significantly increase exercise endurance in animal studies more than either compound .
An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARo compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.
4. GW501516 Function:
GW501516 could be used by athletes as an ergogenic performance enhancing drug that was not
currently controlled by regulations or detected by standard tests. One of the main researchers from the study onenhanced endurance consequently developed a urine test to detect the drug, and made it available to the International Olympic Committee.
5.COA: TEST ITEMS SPECIFICATION RESULTS Description : White Crystalline Powder Light yellow powder Identification : Positive Positive Assay(by HPLC) : 98.0~102.0% 99.84% Absorbance(E1cm) : 465~495 482.5 Melting Point : 191~195¡ãC 193.5~195.0¡ãC Loss On Drying : 0.5%max 0.19% Specific Rotation : +288¡ã~ +298¡ã +290.2¡ã Residue On Ignition : 0.1%max 0.03% Related Substances : Total:1.5%max <1.3% Single:0.5%max <0.4% Residue Solvents : 0.2%max 0.10% Heavy Metals : 20PPm max <10PPm Conclusion The specification conform with enterprise standard.
6.OUR ADWANTAGE: 1, High quality with competitive price: 1) Standard: U.S Standard 2) All Purity≥99.8% 3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery 1) Parcel can be sent out within 8 hours after payment. Tracking number available 2) Secure and discreet shipment. Various transportation methods for your choice. 3) Customs pass rate ≥99.8% 4)We provide re-ship policy. 5) We have warehouse in Australia, Canada and England, we have large amounts of stock in the warehouse, can ship to you directly from our foreign warehouse!
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