Roflumilast for Treatment of Copd CAS: 162401-32-3 White Powder
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- Model NO.: 162401-32-3
- Customized: Customized
- Suitable for: Elderly, Adult
- Purity: >99%
- Sample: Free
- Trademark: LSW
- Specification: USP
- HS Code: 3002205136
- Powder: Yes
- Certification: GMP, ISO 9001
- State: Solid
- Name: Roflumilast
- MOQ: 10 G
- Transport Package: 1 Kg/ Aluminum Foil Bag, 25kgs/Drum
- Origin: China
Product Name: Roflumilast
Synonyms: ROFLUMILAST;3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide;B 9302-107;BY 217;BYK 20869;Daxas;Roflumilast / 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide;3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
Product Categories: All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;APIs;Roflumilast;Daxas;API
Storage temp: Refrigerator
Chemical Properties Crystallin Solid
Usage1: Selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease
Usage2: Roflumilast (Daxas) is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM.
Usage3: ophthalmic solution
Usage4: A selective inhibitor of phosphodiesterase 4.
Roflumilast reduces exacerbations in patients with severe chronic obstructive pulmonary disease. Its effect in patients using fixed combinations of inhaled corticosteroids and longacting β2 agonists is unknown. We postulated that roflumilast would reduce exacerbations in patients with severe chronic obstructive pulmonary disease at risk for exacerbations, even in combination with inhaled corticosteroid and longacting β2 agonist treatment.
Roflumilast is used to control and prevent symptoms (wheezing and shortness of breath) caused by ongoing lung disease (chronic obstructive pulmonary disease-COPD which includes bronchitis). It should be used along with other medications (bronchodilators such as , ipratropium) to treat COPD. It works by reducing the irritation and swelling of the airways. Controlling symptoms of breathing problems can decrease time lost from work or school.
This medication must be used regularly to be effective. It does not work right away and should not be used to relieve sudden shortness of breath or wheezing. If sudden breathing problems occur, use your quick-relief inhaler as prescribed.
How to use roflumilast:
Use roflumilast as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Roflumilast comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get roflumilast refilled.
Take roflumilast by mouth with or without food.
If you miss a dose of roflumilast, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use roflumilast.
Do NOT use roflumilast if:
you are allergic to any ingredient in roflumilast
you have moderate to severe liver problems
you are taking carbamazepine, hydantoins (eg, phenytoin), primidone, rifamycins (eg, rifampin), or St. John's wort
Contact your doctor or health care provider right away if any of these apply to you.
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Back pain; decreased appetite; diarrhea; dizziness; flu-like symptoms; headache; mild weight loss; nausea.
Seek medical attention right away if the side effect necomes worse.
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