USP Top Quality Meprednisone CAS 1247-42-3 Glucocorticoid Anti-Inflammatory for Anti-Allergic
|10-199 200-499 500-999 1,000+|
|FOB Unit Price:||US $1 US $0.9 US $0.8 US $0.7|
|Purchase Qty. (G)||FOB Unit Price|
|Production Capacity:||1000kg/Week and Mass Stock|
|Transport Package:||Disguised Package or as Required Package|
|Payment Terms:||T/T, Western Union, Money Gram, Bitcoin|
- Model NO.: 1247-42-3
- Customized: Non-Customized
- Suitable for: Elderly, Children, Adult
- Purity: >99%
- MW: 372.45
- MOQ: 10g
- Specification: SGS GMP
- HS Code: 3004390090
- Powder: Yes
- Certification: ISO 9001, USP, BP
- State: Solid
- Mf: C22h28o5
- Appearance: White or White Crystalline Powder
- Trademark: LSW
- Origin: China
1. Quick Details:
|Appearance:||White or white crystalline powder|
|Boiling Point(ºC):||574.4°C at 760 mmHg|
|Appearance:||White or white crystalline powder|
|Usage:||Adrenal cortex hormone, the product has anti-inflammatory, anti-allergic, anti toxin, anti-shock, fever and stress the role of|
2. Meprednisone Description:
A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
3. Meprednisone Interactions:
The pharmacokinetic interactions listed below are potentially clinically important. Drugs that induce hepatic enzymes such as , phenytoin and rifampin may increase the clearance of corticosteroids and may require increases in corticosteroid dose to achieve the desired response. Drugs such as troleandomycin and ketoconazole may inhibit the metabolism of corticosteroids and thus decrease their clearance. Therefore, the dose of corticosteroid should be titrated to avoid steroid toxicity. Corticosteroids may increase the clearance of chronic high dose aspirin. This could lead to decreased salicylate serum levels or increase the risk of salicylate toxicity when corticosteroid is withdrawn. Aspirin should be used cautiously in conjunction with corticosteroids in patients suffering from hypoprothrombinemia. The effect of corticosteroids on oral anticoagulants is variable. There are reports of enhanced as well as diminished effects of anticoagulants when given concurrently with corticosteroids. Therefore, coagulation indices should be monitored to maintain the desired anticoagulant effect.
4. How Meprednisone Works:
Glucocorticoids such as Prenolone can inhibit leukocyte infiltration at the site of inflammation, interfere with mediators of inflammatory response, and suppress humoral immune responses. The antiinflammatory actions of glucocorticoids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. Prenolone reduces inflammatory reaction by limiting the capillary dilatation and permeability of the vascular structures. These compounds restrict the accumulation of polymorphonuclear leukocytes and macrophages and reduce the release of vasoactive kinins. Recent research suggests that corticosteroids may inhibit the release of arachidonic acid from phospholipids, thereby reducing the formation of prostaglandins. Prenolone is a glucocorticoid receptor agonist. On binding, the corticoreceptor-ligand complex translocates itself into the cell nucleus, where it binds to many glucocorticoid response elements (GRE) in the promoter region of the target genes. The DNA bound receptor then interacts with basic transcription factors, causing an increase or decrease in expression of specific target genes, including suppression of IL2 (interleukin 2) expression.
5.Uses and Fuction of Meprednisone:
Structure has anti-inflammatory and anti-allergic effects, can inhibit the proliferation of connective tissue, reducing the permeability of the capillary wall and cell membrane, reducing the inflammatory exudate, and can inhibit histamine and other toxic substances formation and release.
This product can promote protein degradation into sugar, reduce glucose utilization. Thus making blood glucose and liver glycogen are increased, there may be diabetes, while increasing gastric secretion, increase appetite.
When severe toxic infection, antimicrobial agents used in conjunction with a large, may have good cooling, anti-drug, anti-inflammatory, anti-shock and promote the role of symptom relief. Its sodium retention and potassium effects than cortisone row of small, strong anti-inflammatory and anti-allergic effects, fewer side effects, it is more commonly used.
6. COA :
|Character||White or almost white crystalline powder|
|Specific rotation||+75 º to +80 º|
|Identification||Complies by IR Complies by TLC|
|Chromatographic purity|| Only one principal impurity more than 1.0% and not more than 2.0. other impurity not |
more than 1.0%
|Loss on drying||Not more than 0.5%|
|Assay||97.0% to 102.0%|
7. Our Adwantage:
High quality with competitive price:
1) Standard: Enterprise Standard
2) All Purity:>=99%
3) We are manufacturer and can provide high quality products with factory price.
Fast and safe delivery:
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate: >=99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
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